A genetically engineered Escherichia coli that senses and degrades tetracycline antibiotic residue
نویسندگان
چکیده
منابع مشابه
Active efflux of tetracycline encoded by four genetically different tetracycline resistance determinants in Escherichia coli.
Tetracycline resistance encoded by four genetically different determinants residing on plasmids in Escherichia coli was shown to be associated in each case with an energy-dependent decrease in accumulation of the antibiotic in whole cells in which resistance had been induced. The different class determinants examined were those on plasmids RP1 (class A), R222 (class B), R144 (class C), and RA1 ...
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متن کاملTetracycline Resistance in Escherichia coli Bearing
1. E8cherichia coli with an R-factor conferring resistance to tetracycline was induced to high-degree resistance by pre-exposure to the antibiotic. The degree of resistance was drastically lowered by subjecting the cells to osmotic shock. 2. Resistance to tetracycline was rapidly restored by incubating the shocked cells in a glucose-salts medium containing shock proteins prepared from tetracycl...
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ژورنال
عنوان ژورنال: Synthetic and Systems Biotechnology
سال: 2018
ISSN: 2405-805X
DOI: 10.1016/j.synbio.2018.05.001